Since the beginning of the AIDS epidemic, I have worked to establish HIV/AIDS research, training, and clinical care programs in the United States and abroad.

In my previous positions at Harvard, I helped create two partnerships with the government of Botswana: the 1996 Botswana-Harvard Partnership with the Harvard AIDS Initiative, where I was executive director, and the African Comprehensive HIV/AIDS Partnerships, an African organization launched in 2000 with funding from the Bill and Melinda Gates and Merck foundations. Also in 2000, I founded the Kitso AIDS Training Program, which would become Botswana’s national AIDS training program.

I was the principal investigator for “The Tshepo Study,” the first large-scale antiretroviral treatment study in southern Africa, funded by the Bristol-Myers Squibb Foundation’s Secure the Future initiative. My research in the region also includes clinical and epidemiological evaluations to help determine how antiretroviral treatment and national treatment programs can best be accomplished in Africa. Since 2000, programs I have created and/or led have trained tens of thousands of health care workers and helped establish national programs on the care, treatment, and prevention of HIV/AIDS in the region.

Following the 2003 launch of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) to combat global HIV/AIDS, the largest commitment by any nation to combat a single disease in history, I was Botswana’s country director for the Botswana-Harvard joint PEPFAR effort. In addition, while serving as scientific director and vice president for implementation at the Elizabeth Glaser Pediatric AIDS Foundation, I was principal investigator of Project HEART, another PEPFAR effort in five African countries. That project began in 2004 and by 2011 had placed more than one million people living with HIV into clinical care sites in Cote d’Ivoire, Mozambique, South Africa, Tanzania, and Zambia. More than 565,000 were placed on life-saving antiretroviral treatment.

I have authored or co-authored more than 140 peer-reviewed articles, in addition to numerous scientific articles and chapters. I have written a textbook, Global AIDS Crisis: A Reference Handbook; and co-edited the book, AIDS in Africa, 2nd Edition. Additionally, I served as chief editor for two special supplements to the journal AIDS and as executive editor of the seminal 320-author, three-volume textbook, From the Ground Up: Building Comprehensive HIV/AIDS Care Programs in Resource Limited Settings.